SomaFleur

The Science of Personalized Wellness

Our approach combines advanced biomarker analysis with expert clinical interpretation to create wellness insights uniquely tailored to your body's needs - no blood work required.

Our Comprehensive Testing Methods

SomaFleur utilizes two gold-standard functional medicine tests to provide the most comprehensive view of your health - all without requiring blood work.

GI-MAP Test
Gut Health Analysis
Comprehensive stool analysis using qPCR technology to assess gut microbiome, pathogens, and digestive function.

What We Analyze:

  • Beneficial Bacteria: Lactobacillus, Bifidobacterium, and other protective microbes
  • Pathogenic Bacteria: H. pylori, C. difficile, and other harmful organisms
  • Parasites & Fungi: Comprehensive screening for intestinal parasites and yeast
  • Digestive Function: Pancreatic enzymes, bile acids, and inflammation markers
  • Intestinal Health: Leaky gut markers, immune function, and gut barrier integrity

Perfect For:

Digestive issues, bloating, IBS, food sensitivities, autoimmune conditions, mood disorders, and anyone wanting to optimize gut health.

DUTCH Plus
Hormone Analysis
Dried Urine Test for Comprehensive Hormones - the most advanced hormone testing available.

What We Analyze:

  • Sex Hormones: Estrogen, progesterone, testosterone and their metabolites
  • Adrenal Function: Cortisol patterns, cortisone, and stress response
  • Melatonin Production: Sleep hormone and circadian rhythm assessment
  • Neurotransmitters: Dopamine and norepinephrine metabolites
  • Nutritional Markers: B12, B6, glutathione, and oxidative stress indicators

Perfect For:

Hormone imbalances, menopause, PCOS, fertility issues, fatigue, sleep problems, mood swings, and metabolic concerns.

No Blood Work Required

Convenient at-home collection using urine and stool samples - no needles, no lab visits.

Trusted by Practitioners

Used by functional medicine practitioners worldwide. Learn about DUTCH validation

Comprehensive Analysis

Together, these tests provide a complete picture of your gut and hormone health.

Latest Research & Findings

Stay updated with the latest scientific discoveries in personalized wellness and functional medicine.

Gut-Hormone Connection

Gut-Brain Axis: Role of Microbiome, Metabolomics, Hormones, and Stress in Mental Health Disorders
August 2024
Peer Reviewed
Verma A, Inslicht SS, Bhargava A. Cells. 2024;13(17):1436. UCSF researchers directly cover the influence of gut microbiome, hormones, and stress on mental health disorders.

Key Findings:

  • • Gut microbiome directly influences mental health outcomes
  • • Metabolomics reveals hormone-gut interactions
  • • Stress pathways mediated through gut-brain connection
Read on PubMed →
Efficacy of Gut Microbiome-Targeted Interventions on Mental Health Symptoms in Women
2025
Meta-Analysis
Healthcare. 2025. A systematic review and meta-analysis of randomized controlled trials examining gut microbiome interventions on mental health in women across hormonal life stages.

Key Findings:

  • • Women-specific mental health improvements documented
  • • Hormonal life stages influence intervention efficacy
  • • Gut microbiome interventions show significant benefits
Read on MDPI →

Estrobolome Studies

Estrogen-Gut Microbiome Axis: Physiological and Clinical Implications
2017
Foundational Research
Baker JM et al. Maturitas. 2017. The foundational estrobolome paper covering how altered circulating estrogens contribute to obesity, metabolic syndrome, cancer, endometriosis, PCOS, cardiovascular disease, and cognitive function.

Key Findings:

  • • Gut microbiome regulates circulating estrogen levels
  • • Links to obesity, PCOS, and metabolic syndrome
  • • Implications for cardiovascular and cognitive health
Read on PubMed →
From Gut to Hormones: Unraveling the Role of Gut Microbiota in (Phyto)Estrogen Modulation
2024
Peer Reviewed
PubMed. 2024. The estrobolome - bacterial genes encoding enzymes like beta-glucuronidases - deconjugates and reactivates estrogen, directly influencing circulating hormone levels.

Key Findings:

  • • Beta-glucuronidases regulate estrogen reactivation
  • • Gut microbiota alterations linked to breast and endometrial cancer
  • • PCOS associations with estrobolome function
Read on PubMed →

LP299V Probiotic Research

Lactiplantibacillus plantarum 299v: Three Decades of Research
2021
Comprehensive Review
PubMed. 2021. LP299V is the most documented Lactobacillus plantarum strain, described in over 170 scientific publications including more than 60 human clinical studies.

Key Findings:

  • • 170+ scientific publications
  • • 60+ human clinical studies
  • • Reduced flatulence and abdominal pain in IBS patients
Read on PubMed →
LP299V Supplementation in Patients with Major Depression - A Metabolomics Study
2025
Clinical Study
PubMed. 2025. Prior research demonstrated improvements in cognitive functions in patients with major depressive disorder supplemented with LP299V alongside standard treatment.

Key Findings:

  • • Cognitive function improvements documented
  • • Supports gut-brain axis positioning
  • • Complements standard depression treatment
Read on PubMed →
LP299V Efficacy in IBS: Double-Blind Randomized Controlled Trial
2001
RCT
PubMed. A randomized placebo-controlled trial demonstrating LP299V efficacy for IBS symptom relief compared to placebo.

Key Findings:

  • • 100% of LP299V patients reported pain resolution vs 55% placebo
  • • 95% overall IBS symptom improvement vs 15% placebo
  • • Double-blind, randomized, placebo-controlled design
Read on PubMed →

Our Dual-System Analysis

SomaFleur's scientific approach is built on understanding the intricate connection between your gut microbiome and hormone system - two systems that work together to regulate your entire body.

The Gut-Hormone Connection

Your gut microbiome directly influences hormone production, metabolism, and elimination. Imbalances in one system inevitably affect the other.

Personalized Recommendations

Based on your unique test results, we provide targeted recommendations that address both systems simultaneously for optimal results.

Ongoing Optimization

We track your progress and adjust your protocol as your body responds and your biomarkers improve.

Frequently Asked Questions

Common questions about our testing methods and scientific approach

Start with Comprehensive Testing

Discover what your gut and hormones reveal about your unique wellness needs with our comprehensive testing approach - no blood work required.