The Science of Precision Wellness

Our approach combines advanced biomarker analysis with expert clinical interpretation to create wellness insights uniquely tailored to your body's needs, every marker benchmarked to what's optimal for women your age.

The 60-Second Version

At SomaFleur, we combine biomarkers, symptoms, and health history to help women better understand their hormonal, metabolic, nutrient, and gut health, professionally interpreted and benchmarked to what's optimal, not just “normal.”

Read the full methodology
What We Measure

Seven body systems. One connected picture.

Most panels look at one system in isolation. We assess 60+ biomarkers across the seven systems that shape how women feel day to day, then read them together, not in silos.

Hormonal Health

Estrogen, progesterone, and testosterone, how they're produced and metabolized, interpreted against your cycle and life stage.

Thyroid Health

A full thyroid picture behind weight, temperature, and fatigue, not just a single TSH value.

Metabolic Health

Glucose, insulin, and how your body manages and stores energy day to day.

Nutrient Status

Iron and ferritin, vitamin D, and B12, the foundations that quietly drive energy, mood, and hair health.

Inflammation

Low-grade inflammatory signals that shape how you feel before they show up as anything else.

Cardiovascular Health

ApoB, lipids, and the markers that matter for the long game, benchmarked to what's optimal.

Gut Health

The microbiome and the gut–hormone axis that connects back to every other system above.

The SomaFleur Method

How we turn data into answers

Testing is only the beginning. Our method rests on three principles that separate a pile of numbers from a picture you can actually act on.

What we measure

Comprehensive testing across seven systems (hormones, gut, metabolic, nutrients, thyroid, inflammation, and cardiovascular) so nothing important is missed.

Our testing philosophy

Every marker is benchmarked against what's optimal for women your age, not just the broad 'normal' range, and read with your cycle in mind.

How we interpret

A specialist clinician interprets your results together and writes a signed SomaFleur Health Intelligence Report with clear, personalized next steps.

Our Comprehensive Testing Methods

SomaFleur combines a comprehensive blood panel with two gold-standard functional medicine tests to provide the most complete view of your health, with hormone and gut samples collected at home and your bloodwork done at a partner lab near you.

GI-MAP Test
Gut Health Analysis
Comprehensive stool analysis using qPCR technology to assess gut microbiome, pathogens, and digestive function.

What We Analyze:

  • Beneficial Bacteria: Lactobacillus, Bifidobacterium, and other protective microbes
  • Pathogenic Bacteria: H. pylori, C. difficile, and other harmful organisms
  • Parasites & Fungi: Comprehensive screening for intestinal parasites and yeast
  • Digestive Function: Pancreatic enzymes, bile acids, and inflammation markers
  • Intestinal Health: Leaky gut markers, immune function, and gut barrier integrity

Perfect For:

Digestive issues, bloating, IBS, food sensitivities, autoimmune conditions, mood disorders, and anyone wanting to optimize gut health.

DUTCH Plus
Hormone Analysis
Dried Urine Test for Comprehensive Hormones - the most advanced hormone testing available.

What We Analyze:

  • Sex Hormones: Estrogen, progesterone, testosterone and their metabolites
  • Adrenal Function: Cortisol patterns, cortisone, and stress response
  • Melatonin Production: Sleep hormone and circadian rhythm assessment
  • Neurotransmitters: Dopamine and norepinephrine metabolites
  • Nutritional Markers: B12, B6, glutathione, and oxidative stress indicators

Perfect For:

Hormone imbalances, menopause, PCOS, fertility issues, fatigue, sleep problems, mood swings, and metabolic concerns.

Convenient Collection

Hormone and gut samples are collected at home, while your bloodwork is done with a quick draw at a partner lab near you, coordinated for you.

Trusted by Practitioners

Used by functional medicine practitioners worldwide. Learn about DUTCH validation

Comprehensive Analysis

Together, these tests provide a complete picture of your gut and hormone health.

Latest Research & Findings

Stay updated with the latest scientific discoveries in personalized wellness and functional medicine.

Gut-Hormone Connection

Gut-Brain Axis: Role of Microbiome, Metabolomics, Hormones, and Stress in Mental Health Disorders
August 2024
Peer Reviewed
Verma A, Inslicht SS, Bhargava A. Cells. 2024;13(17):1436. UCSF researchers directly cover the influence of gut microbiome, hormones, and stress on mental health disorders.

Key Findings:

  • • Gut microbiome directly influences mental health outcomes
  • • Metabolomics reveals hormone-gut interactions
  • • Stress pathways mediated through gut-brain connection
Read on PubMed →
Efficacy of Gut Microbiome-Targeted Interventions on Mental Health Symptoms in Women
2025
Meta-Analysis
Healthcare. 2025. A systematic review and meta-analysis of randomized controlled trials examining gut microbiome interventions on mental health in women across hormonal life stages.

Key Findings:

  • • Women-specific mental health improvements documented
  • • Hormonal life stages influence intervention efficacy
  • • Gut microbiome interventions show significant benefits
Read on MDPI →

Estrobolome Studies

Estrogen-Gut Microbiome Axis: Physiological and Clinical Implications
2017
Foundational Research
Baker JM et al. Maturitas. 2017. The foundational estrobolome paper covering how altered circulating estrogens contribute to obesity, metabolic syndrome, cancer, endometriosis, PCOS, cardiovascular disease, and cognitive function.

Key Findings:

  • • Gut microbiome regulates circulating estrogen levels
  • • Links to obesity, PCOS, and metabolic syndrome
  • • Implications for cardiovascular and cognitive health
Read on PubMed →
From Gut to Hormones: Unraveling the Role of Gut Microbiota in (Phyto)Estrogen Modulation
2024
Peer Reviewed
PubMed. 2024. The estrobolome - bacterial genes encoding enzymes like beta-glucuronidases - deconjugates and reactivates estrogen, directly influencing circulating hormone levels.

Key Findings:

  • • Beta-glucuronidases regulate estrogen reactivation
  • • Gut microbiota alterations linked to breast and endometrial cancer
  • • PCOS associations with estrobolome function
Read on PubMed →

LP299V Probiotic Research

Lactiplantibacillus plantarum 299v: Three Decades of Research
2021
Comprehensive Review
PubMed. 2021. LP299V is the most documented Lactobacillus plantarum strain, described in over 170 scientific publications including more than 60 human clinical studies.

Key Findings:

  • • 170+ scientific publications
  • • 60+ human clinical studies
  • • Reduced flatulence and abdominal pain in IBS patients
Read on PubMed →
LP299V Supplementation in Patients with Major Depression - A Metabolomics Study
2025
Clinical Study
PubMed. 2025. Prior research demonstrated improvements in cognitive functions in patients with major depressive disorder supplemented with LP299V alongside standard treatment.

Key Findings:

  • • Cognitive function improvements documented
  • • Supports gut-brain axis positioning
  • • Complements standard depression treatment
Read on PubMed →
LP299V Efficacy in IBS: Double-Blind Randomized Controlled Trial
2001
RCT
PubMed. A randomized placebo-controlled trial demonstrating LP299V efficacy for IBS symptom relief compared to placebo.

Key Findings:

  • • 100% of LP299V patients reported pain resolution vs 55% placebo
  • • 95% overall IBS symptom improvement vs 15% placebo
  • • Double-blind, randomized, placebo-controlled design
Read on PubMed →

Frequently Asked Questions

Common questions about our testing methods and scientific approach

See the Complete Picture

The Complete Women's Health Blueprint connects foundational bloodwork, hormones, and gut health into one interpreted report, so you understand how your systems work together, not in isolation.