The SomaFleur Journal

Insights, research, and expert guidance on personalized wellness, hormone health, and gut optimization.

Featured Articles

Gut-Brain Axis: Role of Microbiome, Metabolomics, Hormones, and Stress in Mental Health Disorders
Gut Health
UCSF researchers directly cover the influence of gut microbiome, hormones, and stress on mental health disorders. Explores how metabolomics reveals hormone-gut interactions and stress pathways mediated through the gut-brain connection.
Verma A, Inslicht SS, Bhargava A

Verma A, Inslicht SS, Bhargava A

8/15/202412 min read
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Efficacy of Gut Microbiome-Targeted Interventions on Mental Health Symptoms in Women
Gut Health
A systematic review and meta-analysis of randomized controlled trials examining gut microbiome interventions on mental health in women across hormonal life stages. Documents women-specific mental health improvements.
Healthcare Research Team

Healthcare Research Team

1/15/202515 min read
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Estrogen-Gut Microbiome Axis: Physiological and Clinical Implications
Hormones
The foundational estrobolome paper covering how altered circulating estrogens contribute to obesity, metabolic syndrome, cancer, endometriosis, PCOS, cardiovascular disease, and cognitive function.
Baker JM et al.

Baker JM et al.

10/1/201710 min read
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Lactiplantibacillus plantarum 299v: Three Decades of Research
Gut Health
LP299V is the most documented Lactobacillus plantarum strain, described in over 170 scientific publications including more than 60 human clinical studies. Demonstrates reduced flatulence and abdominal pain in IBS patients.
PubMed Research Review

PubMed Research Review

8/1/202114 min read
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Latest Articles

From Gut to Hormones: Unraveling the Role of Gut Microbiota in (Phyto)Estrogen Modulation
Hormones
The estrobolome - bacterial genes encoding enzymes like beta-glucuronidases - deconjugates and reactivates estrogen, directly influencing circulating hormone levels. Links gut microbiota alterations to breast and endometrial cancer, and PCOS.
PubMed Research

PubMed Research

2/15/2024
11 min read
LP299V Supplementation in Patients with Major Depression - A Metabolomics Study
Gut Health
Prior research demonstrated improvements in cognitive functions in patients with major depressive disorder supplemented with LP299V alongside standard treatment. Supports gut-brain axis positioning.
PubMed Clinical Study

PubMed Clinical Study

1/1/2025
9 min read
LP299V Efficacy in IBS: Double-Blind Randomized Controlled Trial
Gut Health
A randomized placebo-controlled trial demonstrating LP299V efficacy for IBS symptom relief. 100% of LP299V patients reported pain resolution vs 55% placebo, and 95% overall IBS symptom improvement vs 15% placebo.
PubMed RCT

PubMed RCT

11/1/2001
8 min read

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